What are the potential side effects?

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Although HA is a natural component of the dermis, its injection may provoke undesired effects depending on variable factors:

  • External: type of product, technique, injected area, number of injections, volume
  • Internal: phototype, medical history, skin tolerance and sensitivity

The side effects are generally benign, reversible and temporary*:

 Onset after injection Side effects  Estimated duration
(1 – 15 days)
  • Hematoma, erythema, oedema
8 days
(15 days – 3 months)
  • Infection (related to conditions of asepsis)
  • Necrosis
  • Non-specific inflammation
 1 – 6 months
(3 – 24 months)
  • Allergy, erythema
  • Pigmentation
 1 – 12 months
Delayed (rare)
(> 3 months – x years)
  • Granuloma
X months – permanent

Non-exhaustive list of side effects associated with the use of injectable wrinkle fillers
Source: ‘‘Topical report – Injectable products to fill wrinkles’’ – The French National Agency for Medicines and Health Products Safety (ANSM) July 2012.

*If you notice side effects after your injection, please contact your practitioner and/or TEOXANE Laboratories.

Category: Teoxane